DescriptionAmisulpride is a selective D2/D3 dopamine receptor antagonist used extensively in behavioral pharmacology and CNS-focused research. This oral formulation allows flexible dosing for animal studies, making it suitable for long-term administration in research settings involving schizophrenia, bipolar disorder, or dopamine modulation. Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications 4 Safety Profile & Handling 5 Core Keywords 6 Research-Use Disclaimer Product SpecificationsParameterDetailsProduct NameAmisulpride Oral SolutionGeneric NameAmisulprideCAS Number71675-85-9Molecular FormulaC??H??N?O?SMolecular Weight369.48?g/molFormulationOral liquid (solution)Strength6?g per 60?ml (100?mg/ml)PackagingBottle with measuring cupDosage FormOral SolutionPack Size1 bottle per boxApproval NumberH20233767 (NMPA China)Drug Code86981979000140ManufacturerZhejiang CONBA Pharmaceutical Co., Ltd.Storage ConditionsStore below 25?°C, protect from lightIntended UseLaboratory research onlyMechanism of ActionAmisulpride selectively blocks dopamine D2 and D3 receptors, especially in the limbic system. At low doses, it modulates presynaptic autoreceptors to increase dopamine release, while at high doses, it reduces postsynaptic signaling—making it unique among antipsychotics for dose-dependent action. It does not bind significantly to serotonin or muscarinic receptors.Research ApplicationsSchizophrenia ModelsAssesses antipsychotic efficacy, dopaminergic modulation, and cognitive function in rodent models of psychosis.Bipolar Disorder & Mood StabilizationStudied in models involving manic-like behavior and dopaminergic hyperactivity.Cognitive & Reward StudiesUseful for experiments involving working memory, reward processing, and behavioral inhibition.PET Imaging & Receptor Binding StudiesD2 receptor occupancy and pharmacokinetics evaluation.Dose-Response PharmacologyOral liquid format ideal for titration studies in various animal species.Safety Profile & HandlingCommon Lab Observations: Hypoactivity, weight changes, and mild GI effects in high doses.Toxicity: Low acute toxicity; avoid overdose in small animal models.Handling: Use with gloves in biosafety cabinets. Avoid ingestion or contact with skin.Shelf Life: 24 months in original sealed packaging.Core KeywordsAmisulpride oral solution, CAS 71675-85-9, dopamine D2 D3 antagonist, schizophrenia research, antipsychotic for lab use, Amisulpride liquid form, CNS pharmacology, wholesale Amisulpride, lab-grade antipsychoticsResearch-Use DisclaimerThis product is supplied strictly for laboratory research use only. It is not approved for human consumption, diagnostic, therapeutic, or veterinary purposes. Use only under institutional biosafety guidelines and proper handling procedures.
