ABT-510 Acetate (CAS 442526-87-6) – High Purity 99.61%

DescriptionABT-510 Acetate is a synthetic nine-amino-acid peptide derived from the type 1 repeat of thrombospondin-1 (TSP-1). It mimics TSP-1’s anti-angiogenic function by binding to CD36 receptors, inducing apoptosis in microvessel endothelial cells, and inhibiting tumor neovascularization. Preclinical studies demonstrate its efficacy in reducing ovarian tumor growth, reducing microvessel density, and enhancing chemotherapy delivery via vascular normalization. Manufactured under GMP conditions with ? 99.61% purity. Contents hide 1 Product Specifications 2 Mechanism of Action & Research Applications 3 Disclaimer Product SpecificationsParameterDetailsProduct NameABT-510 AcetateSynonymsABT-510; TSP-1 mimetic peptideCAS No.442526-87-6Purity? 99.61% (GMP-grade)Molecular FormulaC??H??N??O??Molecular Weight~1054.28 DaAppearanceWhite to off-white solidSolubilitySoluble in water (up to 100 mg/mL with sonication); compatible with DMSOStorage ConditionsStore at –20 °C, dry and light-protectedManufacturing StandardGMP-compliantApplicationsAnti-angiogenesis research, tumor and inflammation modelsRegulatory StatusFor laboratory research use onlyMechanism of Action & Research ApplicationsABT-510 Acetate mimics TSP-1 by binding to CD36 receptors on endothelial cells, triggering caspase-8-dependent apoptosis and inhibiting vascular tube formation. It has demonstrated potent anti-angiogenic effects, tumor growth inhibition, and reduced inflammation in preclinical models including ovarian cancer and inflammatory bowel disease.DisclaimerThis product is intended strictly for laboratory research use only. It is not approved for human or veterinary use. Handle in accordance with institutional safety protocols.