Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling Product SpecificationsAttributeDetailsProduct NameKetorolac Tromethamine Injection (HaiXin®)Generic NameKetorolac TromethamineCAS Number74103?06?3 zh.wikipedia.org 1yao.dxy.cn 1Molecular FormulaC??H??NO?Molecular Weight~255.3?g/mol (ketorolac tromethamine salt)Dosage FormSterile aqueous solution for IV/IM injectionStrength30?mg / 1?mL vialPack Size10 vials per boxApproval NumberChina NMPA H20223467Product Code86981812000030ManufacturerNanjing Hairong Pharmaceutical Co., Ltd.Barcode6973204570058Storage ConditionsStore at 2–25?°C; protect from light and moistureIntended UseLaboratory research onlyMechanism of ActionKetorolac is a non-selective cyclooxygenase (COX?1/COX?2) inhibitor that reduces prostaglandin and thromboxane synthesis. It delivers rapid analgesia and anti-inflammatory effects comparable to opioid strength .Research Applications & PharmacologyAcute Pain Models: Highly effective in preclinical studies of moderate to severe pain (e.g., post-operative, trauma, cancer pain).Analgesia without Opioids: Recommended as a standalone or adjuvant to lessen opioid dosage and associated risks .Administration Routes: Suitable for IV and IM injection; rapid onset (analgesia within 30 minutes; peak effect in 1–2?h; duration ~4–6?h) .Pharmacokinetics: Bioavailability ~100% via injection, half?life 3.5–9?h depending on age, primarily excreted renally (~91%) .Safety Profile & HandlingAdverse Effects: Common GI symptoms (nausea, abdominal pain), dizziness, injection-site discomfort; serious risks include GI bleeding, renal impairment, cardiovascular events, hypersensitivity .Handling Precautions: Use sterile technique; inspect vials for particulates; avoid mixing with certain opioids/antiemetics to prevent precipitation .Contraindications: Not suitable for active ulcers, bleeding disorders, renal/liver impairment, late-stage pregnancy, or combined use with other NSAIDs .Storage: Seal at ?30?°C, shield from light; stable for 24 months ypsm.yzsbh.com.
