Flurbiprofen 50?mg ×?5 Vials Wholesale price comparison

Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 4.1 ?? Research?Use Disclaimer Product SpecificationsAttributeDetailsProduct NameFlurbiprofen Ester Injection (Dishichang®)Generic NameFlurbiprofen Ester (Flurbiprofen Axetil or similar)CAS Number66202?86?6 (flurbiprofen methyl ester)Molecular FormulaC??H??FO? (prodrug ester form)Molecular Weight~258.3 g/molDosage FormInjectable solution (water-soluble lipid-based)Strength50?mg per 5?mL vialPack Size5 vials per boxApproval NumberH20233461 (China NMPA)Product Code86900469000279ManufacturerGuangdong Jiabo Pharmaceutical Co., Ltd.Barcode6937242000250StorageStore at 2–8?°C, protect from lightIntended UseLaboratory research use onlyMechanism of ActionFlurbiprofen ester is a prodrug hydrolyzed in vivo to active flurbiprofen, a non-selective COX-1/COX-2 inhibitor. It reduces prostaglandin synthesis, minimizing inflammation and pain. Being lipophilic enhances distribution in lipid environments and rapid analgesic onset pubchem.ncbi.nlm.nih.gov 13frontiersin.org 13scienceopen.com 13.Research Applications & PharmacologyInflammation & pain models: Effective in fracture pain and arthritic models; intramuscular and intravenous injections suppress markers like CRP, TNF-?, IL?6, COX?1, and COX?2 without muscle necrosis researchgate.net.Perioperative analgesia: Clinically used to relieve pain during procedures like hysterosalpingography eurekalert.org 1researchgate.net 1.Pharmacokinetics: Ester hydrolyzed to flurbiprofen, with racemic isomers (R/S); liposomal formulations enable rapid systemic absorption and CNS penetration; plasma half-life ~4–6 hours; protein binding >99% .Safety Profile & HandlingPreclinical and clinical insights:Low risk of injection-site muscle damage in rats .Common NSAID-related risks: gastrointestinal irritation, renal effects, possible cardiovascular events .Handling guidelines:Use PPE and aseptic technique.Administer by IV/IM slowly, observing for signs of pain or irritation.Monitor biological markers (inflammation, renal/hepatic function).Dispose as pharmaceutical hazardous waste.?? Research?Use DisclaimerThis product is intended solely for laboratory research. It is not approved for clinical, diagnostic, therapeutic, or veterinary applications. Misuse may pose safety hazards and compromise research integrity.