Diclofenac Sodium Sustained?Release 100?mg ×?15 Tablets Wholesale price comparison

Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Key Precautions 4.1 ?? Research?Use Disclaimer Product SpecificationsAttributeDetailsProduct NameDiclofenac Sodium Sustained?Release TabletsGeneric NameDiclofenac SodiumCAS Number15307?86?5 (DrugBank DB00586)Molecular FormulaC14H10Cl2NNaO2Molecular Weight296.15?g/mol (Wikipedia)Dosage FormOral sustained?release tabletStrength100?mg per tabletPack Size15 tablets (5 tablets × 3 boards)Approval NumberH20194038 (China NMPA)Product Code86901206000101ManufacturerLiaoning Fuyuan Pharmaceutical Co., Ltd.Barcode6937463302607StorageStore at room temperature; protect from moisture and lightIntended UseLaboratory research use onlyMechanism of ActionDiclofenac functions by reversibly inhibiting cyclooxygenase enzymes COX-1 and COX-2, reducing prostaglandins (e.g., PGE?) that mediate inflammation, pain, and fever. It also modulates ion channels and reduces leukotriene activity, enhancing its analgesic profile .Research Applications & PharmacologyInflammation and pain models: Effective in osteoarthritis, rheumatoid arthritis, nociception, and postoperative pain studies .Pharmacokinetics:Sustained-release tablets provide extended T_max (~4–8?hrs)High protein binding (>99%); half-life ~1.2–2?hrs.Metabolism: hepatic via CYP2C9; eliminated via urine (~65%) and bile (~35%) as conjugates.Safety Profile & Key PrecautionsAdverse effects: GI irritation (ulceration, bleeding), cardiovascular risk (hypertension, MI, stroke), renal impairment, elevated liver enzymes, headache, dizziness .Handling in models:Monitor renal, hepatic, and cardiovascular markers.Administer with food or buffer to reduce gastric irritation.Dispose of expired medication per hazardous waste protocols.?? Research?Use DisclaimerThis product is intended only for laboratory research. It is neither approved nor intended for diagnostic, therapeutic, clinical, or veterinary use. Misuse may lead to serious side effects, compromise research outcomes, and violate regulations.