Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 4.1 ?? Research?Use Disclaimer Product SpecificationsAttributeDetailsProduct NameDexketoprofen Trometamol InjectionGeneric NameDexketoprofen TrometamolCAS Number(S)-Ketoprofen trometamol salt, proxy for 22071-15-4 en.wikipedia.orgMolecular FormulaC??H??O?·C?H??NO?Molecular Weight~375.4?g/molDosage FormSterile aqueous solution for IV/IM injectionStrength50?mg per 2?mL vialPack Size1 vial per boxApproval NumberH20233636 (China NMPA)Product Code86901599000245ManufacturerNanjing Zhengke Pharmaceutical Co., Ltd.StorageStore at 2–25?°C; protect from lightIntended UseLaboratory research onlyMechanism of ActionDexketoprofen is a selective and reversible inhibitor of COX-1 and COX-2 enzymes, reducing prostaglandin synthesis responsible for pain, inflammation, and fever. It is the pharmacologically active S-enantiomer, offering potent analgesia with a lower required dose and improved tolerability .Research Applications & PharmacologyPostoperative and acute pain models: Shows fast and strong analgesia with opioid-sparing effects .NSAID comparative studies: Superior GI safety profile vs. racemic forms.Pharmacokinetics: Rapid absorption and onset; half-life around 2–3 hours, >99% protein binding; primarily excreted as glucuronide conjugates .Safety Profile & HandlingAdverse effects: Potential for nausea, dizziness, gastrointestinal irritation, injection-site discomfort. Generally well tolerated.Handling guidelines: Use aseptic technique. Monitor for renal and bleeding parameters in animal models. Dispose of waste per chemical safety protocols.?? Research?Use DisclaimerThis product is intended solely for laboratory research. It is not approved for therapeutic, diagnostic, clinical, or veterinary applications. Misuse may result in safety hazards and invalidate experimental outcomes.
