DescriptionEfgartigimod alfa is a neonatal Fc receptor (FcRn) antagonist, designed to reduce pathogenic IgG antibody levels. It’s widely researched in autoimmune disorders, such as myasthenia gravis, immune thrombocytopenia (ITP), and pemphigus vulgaris.This subcutaneous injectable formulation contains 400mg of efgartigimod in a 5.6ml solution. Manufactured by Patheon Italia S.p.A., and approved in China under NMPA SJ20240029 with product code 86984816000020.?? For laboratory research only. Not for clinical, diagnostic, or veterinary use. Contents hide 1 Product Specifications 2 Mechanism & Research Applications 2.1 Common Research Areas: 3 Side Effects (Observed in Research Models) 4 Safety & Handling 5 Core Keywords 6 Research Use Disclaimer Product SpecificationsParameterDetailsProduct NameEfgartigimod Alfa Injection (Subcutaneous)Generic NameEfgartigimod AlfaCAS Number2269744-99-4Molecular ClassHuman IgG1-derived Fc fragment antibodyFormulationInjection (subcutaneous)Strength400mg/5.6mlDosage FormPre-filled vialApproval NumberSJ20240029 (China NMPA)Product Code86984816000020ManufacturerPatheon Italia S.p.A.Packaging1 vial per boxIntended UseFor laboratory research onlyStorage Conditions2–8°C; protect from light, do not freezeMechanism & Research ApplicationsEfgartigimod alfa binds to neonatal Fc receptor (FcRn), interfering with IgG recycling. This leads to increased degradation of circulating pathogenic IgG antibodies — a novel therapeutic mechanism in autoimmune disease research.Common Research Areas:Myasthenia gravis modelsPemphigus and ITP immunopathologyFcRn-mediated IgG homeostasisIgG turnover and half-life studiesFc fusion protein therapeuticsSide Effects (Observed in Research Models)Mild injection site reactionsTransient headache or fatigueIncreased risk of infections under prolonged exposureTransient leukopenia in rodent modelsGastrointestinal disturbances in higher dosingEnsure all use complies with animal ethics and safety standards.Safety & HandlingUse Restriction: Laboratory research use onlyPPE: Gloves, lab coat, goggles requiredStorage: Refrigerate (2–8°C), do not freezeDisposal: Follow chemical and biological waste protocolsCore KeywordsEfgartigimod Alfa injection, FcRn blocker research, 400mg efgartigimod vial, autoimmune IgG inhibitor, Patheon Italia biologics, NMPA SJ20240029, lab-grade efgartigimod, wholesale research antibody modulatorsResearch Use DisclaimerThis product is for experimental research use only. Not for use in humans or animals. Misuse may lead to regulatory or health risks. Always follow institutional biosafety procedures.
