DescriptionAdenosylmethionine (SAMe) is a key endogenous methyl donor involved in transmethylation and trans-sulfuration reactions. Its disulfate tosylate formulation is used in injectable form to protect liver cell membranes, enhance glutathione and coenzyme A synthesis, and facilitate bile flow. Widely utilized in preclinical research on cholestatic hepatitis, liver fibrosis, and metabolic liver injury. Contents hide 1 Adenosylmethionine Disulfate Tosylate Injection Product Specifications 2 Adenosylmethionine Disulfate Tosylate Injection Mechanism of Action 3 Research Application Areas 4 Safety & Handling 5 Core Keywords 6 Research Use Disclaimer Adenosylmethionine Disulfate Tosylate Injection Product SpecificationsParameterDetailsProduct NameAdenosylmethionine Disulfate Tosylate Injection (Baixino)Generic NameS-Adenosyl-L-methionine Disulfate TosylateCAS Number97540?22?2Molecular FormulaC??H??N?O?S·C?H?O?S·2H?SO?Molecular Weight?766.8?g/molDosage FormLyophilized powder for injection with solventDosage per Vial0.5?g SAMe (as disulfate tosylate)Pack Size5 vials 5 vials of provided solventApproval NumberH20193344Drug Standard Code86901523002291ManufacturerCSPC Tianqing Pharmaceutical Group Co., Ltd.BarcodeNot yet assignedStorage ConditionsStore at 2–8?°C, protected from lightIntended UseLaboratory research and preclinical liver function studiesAdenosylmethionine Disulfate Tosylate Injection Mechanism of ActionSAMe acts as a universal methyl group donor in vital biochemical pathways, supporting liver cell membrane integrity, glutathione synthesis, and bile detox pathways. It enhances cellular resilience to oxidative and cholestatic injury .Research Application AreasModels of cholestatic and drug?induced liver injuryPrevention of intrahepatic bile stasis and fibrosisStudies of transmethylation and trans?sulfuration pathwaysEnhancement of antioxidant defenses in hepatocytesComparative research vs. ursodeoxycholic acid in hepatic protectionResearch shows SAMe improves liver tests and reduces fibrosis markers without significant adverse effects in these models ChinaGPDrugBank.Safety & HandlingAdverse Effects: Rare mild gastrointestinal discomfort or sleep disturbances .Reconstitution: Reconstitute each vial with supplied solvent before clinical studies.Handling: Use standard lab PPE—gloves, eyewear, coat; avoid aerosol contact.Storage: Maintain 2–8?°C; do not freeze; protect from light.Core KeywordsAdenosylmethionine disulfate injection, SAMe injection, H20193344, hepatoprotective injection, liver fibrosis research, methyl donor injection, wholesale SAMe vials, lab-grade SAMeResearch Use DisclaimerThis product is strictly for laboratory and preclinical research use. It is not approved for therapeutic, diagnostic, or veterinary applications. Misuse may bear legal and health consequences. Use only under institutional protocols and regulatory oversight.
