Description Contents hide 1 Isepamicin Sulfate Injection Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 5 ?? Research Use Disclaimer Isepamicin Sulfate Injection Product SpecificationsParameterDetailsProduct NameIsepamicin Sulfate Injection (Hongsheng)Generic NameIsepamicin SulfateSynonymsIsepacin, Asepacin, 6?-(Hydroxyaminomethyl)-AmikacinCAS Number— (refer to PubChem Isepamicin Sulfate, CID?3037209)FormulationInjectable solutionStrength0.2?g / 2?mL per vialPack Size10 vials per boxDosage FormIV/IM injection (for research use)Approval NumberNMPA China: H20084625Product Code86904645000060ManufacturerZhejiang Hongsheng Pharmaceutical Co., Ltd.BarcodeNot assigned — contact pharmacistDescriptionClear, colorless solutionStorageRoom temperature, away from lightIntended UseLaboratory research onlyMechanism of ActionIsepamicin is an aminoglycoside antibiotic that binds to the 30S bacterial ribosomal subunit, disrupting protein synthesis. It retains activity against many aminoglycoside-resistant gram?negative bacteria hongshengyy.com 8pubchem.ncbi.nlm.nih.gov 8synapse.patsnap.com 8.Research Applications & PharmacologyStudies of respiratory, urinary, bloodstream, wound, and abdominal infections caused by gram-negative organismsInvestigation of aminoglycoside resistance mechanisms, nephrotoxicity, and ototoxicityDosing in vitro/in vivo models: Adults typically receive 400?mg/day divided doses by IV/IM during preclinical translationSafety Profile & HandlingAdverse Reactions (Preclinical data):Nephrotoxicity (kidney damage) and ototoxicity (hearing loss, tinnitus)Other effects: rash, neuromuscular weakness, GI upset, hematologic changes, injection-site painContraindicated in renal failure or known aminoglycoside hypersensitivity (or family history)Handling Instructions:Use full lab PPE: gloves, coat, gogglesAdminister via IV infusion over ?30?min (or IM) as per research protocolMonitor renal/hearing function in animal modelsDispose compliant with biosafety standards?? Research Use DisclaimerThis product is intended only for laboratory research. Not for therapeutic, clinical, diagnostic, or veterinary use. Improper use may lead to serious health risks and regulatory non-compliance.
