Human Interferon ?2b Vaginal Suppository 500,000 IU × 4 (Shuang Yin Jie / Changchun Institute)

Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Side Effects 5 ?? Research-Use Disclaimer Product SpecificationsParameterDetailsProduct NameHuman Interferon ?2b Vaginal SuppositoryBrand / Chinese NameShuang Yin JieFormulationVaginal suppositoryStrength500,000 IU per suppositoryPack Size4 suppositories per boxDosage FormSuppositoryApproval NumberS20100006 (NMPA, China)Product Code86903320001491ManufacturerChangchun Institute of Biological Products Co., Ltd.BarcodeNot recorded — please contact online pharmacist for assignmentCAS NumberNot specified — varies depending on recombinant sourceStorageStore at 2–8?°C; avoid freezingIntended UseFor laboratory research use onlyMechanism of ActionRecombinant Human Interferon ?2b enhances local immune response by activating interferon receptors on epithelial cells, leading to upregulation of antiviral proteins and inhibition of viral replication. It also modulates cytokine production, contributing to localized anti-inflammatory and immunostimulatory effects.Research Applications & Pharmacology? Research Applications:Experimental models of HPV-related cervical erosionVaginal mucosal immunity studiesCytokine response profiling in epithelial tissuesAnti-inflammatory effects in viral cervicitisAdjunct studies with LEEP or antiviral agents? Pharmacokinetics & Immunodynamics:Onset: Local immune activation within 6–12 hoursBioavailability: Local only; minimal systemic absorptionActivity: IFN-?2b activates STAT1/STAT2 pathway in target cellsMetabolism: Enzymatic degradation at the application siteHalf-life: Short; requires consistent application over 7–10 daysSafety Profile & Side Effects? Observed Reactions in Research Models:Mild transient vaginal irritation or itchingLocal mucosal drynessRare low-grade fever (resolves without treatment)No systemic toxicity at research doses reported? Handling Notes:Wear lab coat, gloves, and protective maskDo not ingest or apply to humans or animalsStore in a refrigerator at 2–8?°C; avoid direct sunlightDispose per institutional biosafety protocol?? Research-Use DisclaimerThis product is intended solely for laboratory research use. It is not authorized for therapeutic, clinical, diagnostic, or veterinary purposes. Improper handling or use in humans may cause harm and violate regulatory guidelines.