Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 5 Core Keywords 6 Research?Use Disclaimer Product SpecificationsSpecificationDetailsProduct NameMacrogol?4000 Powder (ChangWeiKang)Generic NamePolyethylene Glycol?4000 (PEG?4000)CAS Number25322?68?3 en.wikipedia.org 13researchgate.net 13Molecular FormulaH–(OCH?CH?)?–OH, average MW ??4000?DaMolecular Weight3500–4500?g/mol (average ~4000?Da)FormulationWater-soluble powderStrength10?g per sachetPack Size10 sachets per boxApproval NumberH20061086 (NMPA, China)Product Code86901027000106ManufacturerChongqing SinoBio Pharmaceutical Co., Ltd.Barcode6903283400830Storage ConditionsStore at 15–30?°C, in a dry, ventilated place away from lightIntended UseFor laboratory research onlyMechanism of ActionMacrogol?4000 is a non-absorbable, inert osmotic laxative that retains water in the colon by hydrogen bonding, softening stool and improving GI motility. It’s well-tolerated and effective for constipation and bowel preparation models.Research Applications & PharmacologyChronic constipation models: First-line osmotic laxative in preclinical motility studiesBowel preparation: Used in animal models for colon cleansing before endoscopyFormulation science: Excipient studies on solubility, viscosity, and stabilityHydration/electrolyte balance: Ideal for osmotic research owing to negligible absorptionComparative studies: Demonstrated higher efficacy and tolerability vs. lactulose, with less gas/flatulenceSafety Profile & HandlingSafety: High molecular weight PEG is biologically inert and well tolerated; minimal systemic absorption (<4%)Possible effects: May cause mild bloating, abdominal pain, diarrheaLaboratory precautions: Use standard PPE; avoid inhalation of powder; weigh and dissolve with lab-grade waterStorage: Keep in a dry area at room temperature, protected from moistureDisposal: Dispose of unused powder and solutions per chemical waste protocolsCore Keywordsmacrogol 4000 powder, PEG 4000 research, osmotic laxative powder, CAS?25322?68?3, chronic constipation model, bowel prep research, ChangWeiKang macrogol, wholesale PEG 4000Research?Use DisclaimerThis product is intended only for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary use. Improper use may pose health risks. Please follow institutional safety protocols.
