Bumetanide Injection 0.5mg/2ml (Research Grade) – For Laboratory Use Only

DescriptionBumetanide is a potent loop diuretic that inhibits the Na/K/2Cl symporter in the thick ascending limb of the loop of Henle. It is used in research involving fluid and electrolyte balance, kidney function, hypertension, and heart failure models.This injectable formulation contains 0.5mg of Bumetanide per 2ml vial, with 5 vials per box. It is widely employed in pharmacodynamic and pharmacokinetic studies of diuretics and renal function modulators.Approved by the China NMPA (H20057376) and manufactured by Henan Xintai Pharmaceutical Co., Ltd.For laboratory research use only. Not for clinical or human use. Contents hide 1 Product Specifications 2 Mechanism of Action & Research Applications 3 Safety & Handling 4 Research Use Disclaimer Product SpecificationsParameterDetailsProduct NameBumetanide InjectionGeneric NameBumetanideCAS Number28395-03-1Molecular FormulaC17H20N2O5SMolecular Weight364.42 g/molDosage FormInjectionStrength0.5mg/2mlQuantity5 vials per boxApproval NumberH20057376 (China NMPA)Product Code86903091000334ManufacturerHenan Xintai Pharmaceutical Co., Ltd.Barcode6974351310061Intended UseFor laboratory research use onlyStorage ConditionsStore below 25°C, away from light and moistureMechanism of Action & Research ApplicationsBumetanide selectively inhibits the Na-K-2Cl cotransporter (NKCC2) in the loop of Henle, leading to significant diuresis and natriuresis. In laboratory settings, it is often used to model fluid retention disorders, renal dysfunction, loop diuretic response, and electrolyte imbalances.It is also studied in neurodevelopmental and epilepsy research due to its influence on chloride transport in neurons.Safety & HandlingUse Restriction: For research use only. Not for human or animal use.Protective Equipment: Wear gloves, lab coat, and eye protection when handling.Storage: Store in original packaging, sealed, below 25°C.Disposal: Follow chemical waste disposal regulations.Research Use DisclaimerThis product is intended exclusively for laboratory research. It is not approved for use in humans or animals. Misuse may pose health or legal risks. Use only in certified research facilities under proper supervision.